Description

Adderall XR 25mg: Complete Guide to This ADHD Medication

Adderall XR 25mg is a high-strength, extended-release formulation of mixed amphetamine salts, a central nervous system (CNS) stimulant used to treat Attention Deficit Hyperactivity Disorder (ADHD) in adults and children aged 6 years and older . It is a Schedule II controlled substance with a high potential for abuse and dependence . For more information on ADHD treatment options and medication management, visit our website.

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Product Identification

Adderall XR 25mg capsules are distinct and identifiable by the following physical characteristics :

Composition

Each 25 mg capsule contains a combination of four active ingredients in equal portions :

• Dextroamphetamine Saccharate (6.25 mg)

• Amphetamine Aspartate Monohydrate (6.25 mg)

• Dextroamphetamine Sulfate USP (6.25 mg)

• Amphetamine Sulfate USP (6.25 mg)

The total amphetamine base equivalence for the 25 mg strength is 15.6 mg .

Inactive Ingredients

The 25mg capsule contains methacrylic acid – methyl methacrylate copolymer (1:1), sucrose, magnesium silicate, triethyl citrate, ferric oxide red, titanium dioxide, and ferric oxide yellow .

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How Adderall XR Works

Adderall XR is a CNS stimulant that works by increasing the activity of certain neurotransmitters in the brain, specifically dopamine and norepinephrine . The extended-release capsule contains two types of drug-containing beads designed to give a double-pulsed delivery of amphetamines, providing a prolonged effect with a single morning dose . This once-daily dosing helps manage ADHD symptoms throughout the day .

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Primary Uses

Adderall XR is FDA-approved for the treatment of ADHD :

• Children (ages 6-12): Efficacy established in clinical trials 

• Adolescents (ages 13-17): Efficacy established in clinical trials 

• Adults: Efficacy established in clinical trials 

For more information on ADHD treatment and other medication options, explore our resources.

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Dosage and Administration

Recommended Dosing

General Administration Guidelines

• Timing: Take once daily in the morning when you first wake up . Avoid afternoon doses as they may cause insomnia .

• Swallowing: Swallow capsules whole with water. Do not crush or chew the capsules .

• Alternative Administration: If you cannot swallow the capsule, open it and sprinkle the contents over a spoonful of applesauce. Swallow the mixture immediately without chewing, followed by a drink of water .

• With or Without Food: May be taken with or without food, but consistency matters .

You can learn more about ADHD medication dosage and titration from our resources.

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Important Safety Information

Boxed Warning: Abuse, Misuse, and Addiction

Adderall XR has a high potential for abuse, misuse, and addiction, which can lead to overdose and death . The medication can be habit-forming and should only be used as prescribed. Assess the risk of abuse before prescribing and monitor for signs of abuse and dependence during therapy .

Contraindications

Do not take Adderall XR if you have :

• Advanced arteriosclerosis

• Symptomatic cardiovascular disease

• Moderate to severe hypertension

• Hyperthyroidism

• Glaucoma

• Agitated states

• History of drug abuse

• Known hypersensitivity to amphetamine

• Taken a monoamine oxidase inhibitor (MAOI) within the past 14 days

Warnings and Precautions

• Serious Cardiovascular Events: Sudden death has been reported in children and adolescents with structural cardiac abnormalities taking usual doses; sudden death, stroke, and myocardial infarction have been reported in adults .

• Increased Blood Pressure and Heart Rate: Monitor blood pressure and pulse at appropriate intervals .

• Psychiatric Adverse Events: Stimulants may cause new or worsened psychotic or manic symptoms .

• Long-Term Suppression of Growth: Monitor height and weight in pediatric patients .

• Seizures: May lower the convulsive threshold. Discontinue in the presence of seizures .

• Peripheral Vasculopathy (Raynaud’s Phenomenon): Careful observation for digital changes is necessary .

• Serotonin Syndrome: Increased risk when coadministered with serotonergic agents (SSRIs, SNRIs, triptans) .

• Visual Disturbance: Blurred vision has been reported .

• Tics: May exacerbate tics. Evaluate for tics and Tourette’s syndrome prior to use .

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Potential Side Effects

Common Side Effects in Children (6-12 years)

Loss of appetite, insomnia, abdominal pain, emotional lability, vomiting, nervousness, nausea, and fever .

Common Side Effects in Adolescents (13-17 years)

Loss of appetite, insomnia, abdominal pain, weight loss, and nervousness .

Common Side Effects in Adults

Dry mouth, loss of appetite, insomnia, headache, weight loss, nausea, anxiety, agitation, dizziness, tachycardia, diarrhea, asthenia, and urinary tract infections .

Other Reported Side Effects

Constipation, decreased interest in sexual activity, drowsiness, grinding teeth, irritability, mood changes, stomach ache, sweating, and thirst .

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Drug Interactions

• MAOIs: Contraindicated. Do not administer within 14 days of stopping MAOI .

• Serotonergic Drugs: Increased risk of serotonin syndrome .

• CYP2D6 Inhibitors: May increase exposure and risk of serotonin syndrome .

• Urinary Alkalinizing Agents (Antacids): Increase blood levels and potentiate amphetamine action. Avoid coadministration .

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Frequently Asked Questions

What is Adderall XR 25mg used for?
Adderall XR 25mg is used to treat ADHD in adults and children aged 6 years and older .

What does Adderall XR 25mg look like?
Adderall XR 25mg capsules are orange & white, capsule/oblong in shape, 21mm in size, with the imprint “ADDERALL XR 25 mg” .

What is the maximum dose of Adderall XR for children?
The maximum Adderall XR dosage for children ages 6 to 12 years is 30 mg daily .

How should I take Adderall XR?
Take it once daily in the morning. Swallow the capsule whole, or open it and sprinkle the contents over applesauce. Avoid afternoon doses .

Is Adderall XR a controlled substance?
Yes, Adderall XR is classified as a Schedule II controlled substance due to its high potential for abuse and dependence .

For authoritative information, visit:

• U.S. Food and Drug Administration (FDA)

• National Institute of Mental Health (NIMH): ADHD

• DailyMed: Adderall XR Label